T45S (p.Thr45Ser) variant of TNF (Tumor necrosis factor)
T45S (p.Thr45Ser) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
T45S (p.Thr45Ser) variant details
- p.Thr45Ser
- 1000Genomes rs948780599
- Missense
- Variant Prioritization Score for Impact Estimate 0.566
- REVEL 0.50
- CADD 23.40
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available