T3A (p.Thr3Ala) variant of TNF (Tumor necrosis factor)
T3A (p.Thr3Ala) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
T3A (p.Thr3Ala) variant details
- p.Thr3Ala
- gnomAD rs1771144082
- Missense
- Variant Prioritization Score for Impact Estimate 0.526
- REVEL 0.45
- CADD 25.50
- PolyPhen-2 0.46
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available