T21I (p.Thr21Ile) variant of TNF (Tumor necrosis factor)
T21I (p.Thr21Ile) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
T21I (p.Thr21Ile) variant details
- p.Thr21Ile
- TOPMed rs1160009797
- gnomAD rs1160009797
- Missense
- Variant Prioritization Score for Impact Estimate 0.201
- REVEL 0.10
- CADD 17.20
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available