S80P (p.Ser80Pro) variant of TNF (Tumor necrosis factor)
S80P (p.Ser80Pro) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
S80P (p.Ser80Pro) variant details
- p.Ser80Pro
- ESP rs369783162
- ExAC rs369783162
- TOPMed rs369783162
- gnomAD rs369783162
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.41
- CADD 23.50
- PolyPhen-2 0.82
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 7.2e-06)
- Structural context available