S5R (p.Ser5Arg) variant of TNF (Tumor necrosis factor)
S5R (p.Ser5Arg) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
S5R (p.Ser5Arg) variant details
- p.Ser5Arg
- ExAC rs747694851
- TOPMed rs747694851
- gnomAD rs747694851
- Missense
- Variant Prioritization Score for Impact Estimate 0.484
- REVEL 0.37
- CADD 26.40
- PolyPhen-2 0.61
- SIFT 0.02
- Most common in the South Asian population (allele frequency 3.6e-05)
- Structural context available