S5N (p.Ser5Asn) variant of TNF (Tumor necrosis factor)
S5N (p.Ser5Asn) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
S5N (p.Ser5Asn) variant details
- p.Ser5Asn
- ExAC rs771650207
- gnomAD rs771650207
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.17
- CADD 17.70
- PolyPhen-2 0.01
- SIFT 0.27
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available