S34R (p.Ser34Arg) variant of TNF (Tumor necrosis factor)
S34R (p.Ser34Arg) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
S34R (p.Ser34Arg) variant details
- p.Ser34Arg
- TOPMed rs1418646618
- gnomAD rs1418646618
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- REVEL 0.65
- CADD 23.60
- PolyPhen-2 0.87
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.00012)
- Structural context available