S2N (p.Ser2Asn) variant of TNF (Tumor necrosis factor)
S2N (p.Ser2Asn) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
S2N (p.Ser2Asn) variant details
- p.Ser2Asn
- 1000Genomes rs2150388436
- Missense
- Variant Prioritization Score for Impact Estimate 0.568
- REVEL 0.41
- CADD 26.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the 1KG:IBS population (allele frequency 0.0048)
- Structural context available