R8Q (p.Arg8Gln) variant of TNF (Tumor necrosis factor)
R8Q (p.Arg8Gln) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
R8Q (p.Arg8Gln) variant details
- p.Arg8Gln
- 1000Genomes rs201502336
- ExAC rs201502336
- TOPMed rs201502336
- gnomAD rs201502336
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.17
- CADD 21.80
- PolyPhen-2 0.01
- SIFT 0.27
- Most common in the 1KG:ASW population (allele frequency 0.0098)
- Structural context available