R8P (p.Arg8Pro) variant of TNF (Tumor necrosis factor)
R8P (p.Arg8Pro) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R8P (p.Arg8Pro) variant details
- p.Arg8Pro
- 1000Genomes rs201502336
- ExAC rs201502336
- TOPMed rs201502336
- gnomAD rs201502336
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.46
- CADD 23.70
- PolyPhen-2 0.75
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available