R78K (p.Arg78Lys) variant of TNF (Tumor necrosis factor)
R78K (p.Arg78Lys) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
R78K (p.Arg78Lys) variant details
- p.Arg78Lys
- Ensembl rs1771201159
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.34
- CADD 23.10
- PolyPhen-2 0.01
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available