R78G (p.Arg78Gly) variant of TNF (Tumor necrosis factor)
R78G (p.Arg78Gly) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
R78G (p.Arg78Gly) variant details
- p.Arg78Gly
- ExAC rs775365890
- gnomAD rs775365890
- Missense
- Variant Prioritization Score for Impact Estimate 0.368
- REVEL 0.31
- CADD 21.90
- PolyPhen-2 0.01
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available