R60K (p.Arg60Lys) variant of TNF (Tumor necrosis factor)
R60K (p.Arg60Lys) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
R60K (p.Arg60Lys) variant details
- p.Arg60Lys
- gnomAD 6-31575920-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.139
- REVEL 0.07
- CADD 10.80
- PolyPhen-2 0.00
- SIFT 0.84
- Most common in the REMAINING population (allele frequency 1.8e-05)
- Structural context available
- Literature evidence available