R60G (p.Arg60Gly) variant of TNF (Tumor necrosis factor)
R60G (p.Arg60Gly) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
R60G (p.Arg60Gly) variant details
- p.Arg60Gly
- gnomAD rs1213638600
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.15
- CADD 18.60
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available