R29Q (p.Arg29Gln) variant of TNF (Tumor necrosis factor)
R29Q (p.Arg29Gln) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
R29Q (p.Arg29Gln) variant details
- p.Arg29Gln
- 1000Genomes rs576621666
- ExAC rs576621666
- TOPMed rs576621666
- gnomAD rs576621666
- Missense
- Variant Prioritization Score for Impact Estimate 0.371
- REVEL 0.41
- CADD 22.70
- PolyPhen-2 0.63
- SIFT 0.02
- Most common in the 1KG:ITU population (allele frequency 0.0049)
- Structural context available