R28K (p.Arg28Lys) variant of TNF (Tumor necrosis factor)
R28K (p.Arg28Lys) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
R28K (p.Arg28Lys) variant details
- p.Arg28Lys
- TOPMed rs1192279581
- gnomAD rs1192279581
- Missense
- Variant Prioritization Score for Impact Estimate 0.203
- REVEL 0.09
- CADD 12.60
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available