Q75E (p.Gln75Glu) variant of TNF (Tumor necrosis factor)
Q75E (p.Gln75Glu) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
Q75E (p.Gln75Glu) variant details
- p.Gln75Glu
- gnomAD 6-31576570-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.34
- CADD 16.40
- PolyPhen-2 0.01
- SIFT 0.29
- Population evidence available
- Structural context available
- Literature evidence available