Q59R (p.Gln59Arg) variant of TNF (Tumor necrosis factor)
Q59R (p.Gln59Arg) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
Q59R (p.Gln59Arg) variant details
- p.Gln59Arg
- TOPMed rs1485010267
- gnomAD rs1485010267
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.42
- CADD 26.40
- PolyPhen-2 0.55
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available