Q25E (p.Gln25Glu) variant of TNF (Tumor necrosis factor)
Q25E (p.Gln25Glu) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
Q25E (p.Gln25Glu) variant details
- p.Gln25Glu
- ExAC rs764955335
- gnomAD rs764955335
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.24
- CADD 16.70
- PolyPhen-2 0.14
- SIFT 0.22
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available