P64L (p.Pro64Leu) variant of TNF (Tumor necrosis factor)
P64L (p.Pro64Leu) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
P64L (p.Pro64Leu) variant details
- p.Pro64Leu
- ExAC rs35131721
- TOPMed rs35131721
- gnomAD rs35131721
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.16
- CADD 9.85
- PolyPhen-2 0.01
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 5.9e-05)
- Structural context available