P58S (p.Pro58Ser) variant of TNF (Tumor necrosis factor)
P58S (p.Pro58Ser) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
P58S (p.Pro58Ser) variant details
- p.Pro58Ser
- gnomAD 6-31575913-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.652
- REVEL 0.55
- CADD 26.50
- PolyPhen-2 0.98
- SIFT 0.13
- Population evidence available
- Structural context available
- Literature evidence available