P24T (p.Pro24Thr) variant of TNF (Tumor necrosis factor)
P24T (p.Pro24Thr) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
P24T (p.Pro24Thr) variant details
- p.Pro24Thr
- ExAC rs754639425
- TOPMed rs754639425
- gnomAD rs754639425
- Missense
- Variant Prioritization Score for Impact Estimate 0.233
- REVEL 0.20
- CADD 18.50
- PolyPhen-2 0.46
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available