P18S (p.Pro18Ser) variant of TNF (Tumor necrosis factor)
P18S (p.Pro18Ser) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
P18S (p.Pro18Ser) variant details
- p.Pro18Ser
- gnomAD rs1375111873
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.09
- CADD 6.50
- PolyPhen-2 0.00
- SIFT 0.43
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available