M6V (p.Met6Val) variant of TNF (Tumor necrosis factor)
M6V (p.Met6Val) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
M6V (p.Met6Val) variant details
- p.Met6Val
- gnomAD 6-31575757-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.505
- REVEL 0.41
- CADD 24.80
- PolyPhen-2 0.62
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available