L73P (p.Leu73Pro) variant of TNF (Tumor necrosis factor)
L73P (p.Leu73Pro) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
L73P (p.Leu73Pro) variant details
- p.Leu73Pro
- TOPMed rs956294956
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.46
- CADD 23.00
- PolyPhen-2 0.03
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available