L69V (p.Leu69Val) variant of TNF (Tumor necrosis factor)
L69V (p.Leu69Val) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
L69V (p.Leu69Val) variant details
- p.Leu69Val
- ExAC rs759609722
- TOPMed rs759609722
- gnomAD rs759609722
- Missense
- Variant Prioritization Score for Impact Estimate 0.115
- REVEL 0.14
- CADD 2.93
- PolyPhen-2 0.01
- SIFT 0.34
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available