L51M (p.Leu51Met) variant of TNF (Tumor necrosis factor)
L51M (p.Leu51Met) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
L51M (p.Leu51Met) variant details
- p.Leu51Met
- gnomAD 6-31575892-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.554
- REVEL 0.59
- CADD 24.80
- PolyPhen-2 1.00
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available