L50M (p.Leu50Met) variant of TNF (Tumor necrosis factor)
L50M (p.Leu50Met) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
L50M (p.Leu50Met) variant details
- p.Leu50Met
- gnomAD 6-31575889-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.49
- REVEL 0.54
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available