L35F (p.Leu35Phe) variant of TNF (Tumor necrosis factor)
L35F (p.Leu35Phe) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
L35F (p.Leu35Phe) variant details
- p.Leu35Phe
- gnomAD 6-31575844-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.434
- REVEL 0.45
- CADD 15.10
- PolyPhen-2 0.11
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available