L17V (p.Leu17Val) variant of TNF (Tumor necrosis factor)
L17V (p.Leu17Val) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
L17V (p.Leu17Val) variant details
- p.Leu17Val
- gnomAD rs1395544606
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.29
- CADD 13.90
- PolyPhen-2 0.37
- SIFT 0.39
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available