K20E (p.Lys20Glu) variant of TNF (Tumor necrosis factor)
K20E (p.Lys20Glu) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
K20E (p.Lys20Glu) variant details
- p.Lys20Glu
- gnomAD rs1326672610
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- REVEL 0.29
- CADD 20.30
- PolyPhen-2 0.05
- SIFT 0.46
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available