K19T (p.Lys19Thr) variant of TNF (Tumor necrosis factor)
K19T (p.Lys19Thr) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
K19T (p.Lys19Thr) variant details
- p.Lys19Thr
- 1000Genomes rs377338702
- ESP rs377338702
- ExAC rs377338702
- TOPMed rs377338702
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.22
- CADD 17.70
- PolyPhen-2 0.22
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available