K19E (p.Lys19Glu) variant of TNF (Tumor necrosis factor)
K19E (p.Lys19Glu) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
K19E (p.Lys19Glu) variant details
- p.Lys19Glu
- gnomAD 6-31575796-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.13
- CADD 19.70
- PolyPhen-2 0.01
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available