H52Q (p.His52Gln) variant of TNF (Tumor necrosis factor)
H52Q (p.His52Gln) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
H52Q (p.His52Gln) variant details
- p.His52Gln
- Ensembl rs1562479959
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.36
- CADD 18.90
- PolyPhen-2 0.02
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available