G57D (p.Gly57Asp) variant of TNF (Tumor necrosis factor)
G57D (p.Gly57Asp) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
G57D (p.Gly57Asp) variant details
- p.Gly57Asp
- gnomAD 6-31575911-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.689
- REVEL 0.62
- CADD 25.90
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available