G26S (p.Gly26Ser) variant of TNF (Tumor necrosis factor)
G26S (p.Gly26Ser) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
G26S (p.Gly26Ser) variant details
- p.Gly26Ser
- gnomAD 6-31575817-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.16
- CADD 18.40
- PolyPhen-2 0.04
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available