G23V (p.Gly23Val) variant of TNF (Tumor necrosis factor)
G23V (p.Gly23Val) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
G23V (p.Gly23Val) variant details
- p.Gly23Val
- gnomAD rs1234547532
- Missense
- Variant Prioritization Score for Impact Estimate 0.458
- REVEL 0.30
- CADD 23.00
- PolyPhen-2 0.77
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available