G23R (p.Gly23Arg) variant of TNF (Tumor necrosis factor)
G23R (p.Gly23Arg) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
G23R (p.Gly23Arg) variant details
- p.Gly23Arg
- gnomAD rs1353047835
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.29
- CADD 25.50
- PolyPhen-2 0.90
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available