G22W (p.Gly22Trp) variant of TNF (Tumor necrosis factor)
G22W (p.Gly22Trp) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
G22W (p.Gly22Trp) variant details
- p.Gly22Trp
- gnomAD 6-31575805-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.07
- CADD 17.60
- PolyPhen-2 0.01
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available