G22R (p.Gly22Arg) variant of TNF (Tumor necrosis factor)
G22R (p.Gly22Arg) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
G22R (p.Gly22Arg) variant details
- p.Gly22Arg
- ExAC rs753713562
- gnomAD rs753713562
- Missense
- Variant Prioritization Score for Impact Estimate 0.147
- REVEL 0.07
- CADD 12.70
- PolyPhen-2 0.01
- SIFT 0.87
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available