E62G (p.Glu62Gly) variant of TNF (Tumor necrosis factor)
E62G (p.Glu62Gly) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
E62G (p.Glu62Gly) variant details
- p.Glu62Gly
- ExAC rs765178016
- gnomAD rs765178016
- Missense
- Variant Prioritization Score for Impact Estimate 0.487
- REVEL 0.34
- CADD 32.00
- PolyPhen-2 0.82
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available