E62D (p.Glu62Asp) variant of TNF (Tumor necrosis factor)
E62D (p.Glu62Asp) in TNF (Tumor necrosis factor) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
E62D (p.Glu62Asp) variant details
- p.Glu62Asp
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.552
- REVEL 0.35
- CADD 32.00
- PolyPhen-2 0.67
- SIFT 0.08
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available