E61Q (p.Glu61Gln) variant of TNF (Tumor necrosis factor)
E61Q (p.Glu61Gln) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
E61Q (p.Glu61Gln) variant details
- p.Glu61Gln
- gnomAD rs1258319339
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.28
- CADD 24.30
- PolyPhen-2 0.50
- SIFT 0.10
- Most common in the Finnish in Finland (FIN) population (allele frequency 9.4e-05)
- Structural context available