E61K (p.Glu61Lys) variant of TNF (Tumor necrosis factor)
E61K (p.Glu61Lys) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
E61K (p.Glu61Lys) variant details
- p.Glu61Lys
- gnomAD rs1258319339
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.27
- CADD 23.40
- PolyPhen-2 0.24
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available