E4G (p.Glu4Gly) variant of TNF (Tumor necrosis factor)
E4G (p.Glu4Gly) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
E4G (p.Glu4Gly) variant details
- p.Glu4Gly
- gnomAD rs1445719601
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- REVEL 0.43
- CADD 28.60
- PolyPhen-2 0.87
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available