D9E (p.Asp9Glu) variant of TNF (Tumor necrosis factor)
D9E (p.Asp9Glu) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
D9E (p.Asp9Glu) variant details
- p.Asp9Glu
- gnomAD 6-31575768-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.46
- CADD 18.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available