A44T (p.Ala44Thr) variant of TNF (Tumor necrosis factor)
A44T (p.Ala44Thr) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
A44T (p.Ala44Thr) variant details
- p.Ala44Thr
- TOPMed rs867435711
- gnomAD rs867435711
- Missense
- Variant Prioritization Score for Impact Estimate 0.576
- REVEL 0.43
- CADD 25.30
- PolyPhen-2 0.88
- SIFT 0.00
- Most common in the HGDP:HAN population (allele frequency 0.015)
- Structural context available