A16V (p.Ala16Val) variant of TNF (Tumor necrosis factor)
A16V (p.Ala16Val) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
A16V (p.Ala16Val) variant details
- p.Ala16Val
- ExAC rs763000109
- gnomAD rs763000109
- Missense
- Variant Prioritization Score for Impact Estimate 0.0999
- REVEL 0.12
- CADD 1.00
- PolyPhen-2 0.01
- SIFT 0.60
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available