A16G (p.Ala16Gly) variant of TNF (Tumor necrosis factor)
A16G (p.Ala16Gly) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
A16G (p.Ala16Gly) variant details
- p.Ala16Gly
- ExAC rs763000109
- gnomAD rs763000109
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.23
- CADD 9.90
- PolyPhen-2 0.30
- SIFT 0.05
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available