A13D (p.Ala13Asp) variant of TNF (Tumor necrosis factor)
A13D (p.Ala13Asp) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
A13D (p.Ala13Asp) variant details
- p.Ala13Asp
- gnomAD 6-31575779-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.556
- REVEL 0.52
- CADD 24.20
- PolyPhen-2 0.76
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available